Ghanaian universities possess a significant, yet largely unused, resource in the form of completed postgraduate theses. These extensive research projects, representing years of student work, are typically archived and rarely revisited after examination. The author argues this represents a missed opportunity for economic and societal benefit, as the research contains potentially valuable ideas for businesses, policies, and new products. Currently, neither the students who create the work nor the universities that support it financially profit from these findings. This systemic issue highlights a lack of mechanisms for identifying, funding, and commercializing the intellectual property generated within Ghanaian higher education. The author frames the situation as a “vault with no key,” emphasizing the lost potential for innovation and economic growth. Addressing this could unlock a new avenue for development and reward academic endeavor.