Chronic kidney disease is increasingly prevalent in Guatemala, posing a significant public health challenge. The country reports 64 cases per 100,000 inhabitants, indicating a substantial burden of the disease. Notably, the condition is affecting a growing number of young people, disrupting the lives of thousands of families nationwide. The rise in cases signals a concerning trend, prompting calls for increased awareness and preventative measures. The causes of this surge are currently under investigation, but factors like dehydration in agricultural workers are suspected. This “silent epidemic” demands urgent attention and resources to mitigate its impact on the population and healthcare system.