The United States estimates a high number of casualties following the recent earthquake in Venezuela, with potential losses equivalent to 2% of the country’s GDP. US officials report that a majority of Venezuelan residents live in structures highly vulnerable to earthquake damage. While some buildings incorporate earthquake-resistant features, unreinforced brick masonry remains prevalent and poses a significant risk. The extent of the damage suggests widespread structural failures. Further assessments are underway to determine the full scope of the devastation and the precise number of victims. The earthquake’s impact is expected to exacerbate existing economic challenges within Venezuela.