An investigation by CBC News has revealed a concerning trend: the vast majority of serious adverse reactions among plasma donors in the last decade occurred at for-profit plasma collection centers. Data indicates multiple donors experienced life-threatening conditions, requiring hospitalization or further medical care following donations. The findings raise questions about safety protocols and oversight at these facilities compared to non-profit donation sites. While plasma donation is generally safe, the data suggests a disproportionate risk associated with for-profit centers. Health Canada is aware of the data and is reviewing it, but has not yet indicated any planned changes to regulations. The investigation highlights the need for increased scrutiny and potential improvements in safety standards within the plasma donation industry. Further investigation is ongoing to determine the specific causes of these adverse reactions.