Nigerian medical experts are warning of a significant increase in liver disease cases directly linked to widespread self-medication practices. The unregulated use of painkillers, antibiotics, and herbal remedies, often taken without professional diagnosis or oversight, is identified as the primary driver of this health crisis. Experts express concern that millions of Nigerians are unknowingly risking irreversible liver damage through this practice. The indiscriminate consumption of these medications bypasses necessary medical evaluations, leading to misdiagnosis and inappropriate treatment. This trend places a substantial strain on the healthcare system and poses a serious public health threat. Authorities are urged to address the issue through public awareness campaigns and stricter regulation of medication access.