The Manado Food and Drug Agency (BBPOM) in North Sulawesi, Indonesia, has reported ongoing instances of pharmacies dispensing antibiotics without a doctor’s prescription. This practice is considered highly concerning, as it contributes to the growing problem of antimicrobial resistance. BBPOM Manado officials emphasize the dangers of self-medication with antibiotics, potentially leading to ineffective treatment in the future. Uncontrolled antibiotic use weakens the body’s ability to fight off infections. The agency is actively monitoring pharmacies in the Manado area to address the issue and ensure compliance with regulations. Further action will be taken against pharmacies found violating prescription requirements. This situation poses a significant public health risk in North Sulawesi.