The large-scale Lifelines population study, one of the biggest in Europe, is recruiting new participants for the first time in twenty years. Since 2006, the research has tracked the health of over 167,000 residents of Groningen, Friesland, and Drenthe, aiming to understand healthy aging. Participants undergo medical measurements, blood draws, and complete digital questionnaires, with data being used anonymously by researchers globally for studies on hereditary diseases, obesity, and mental health. Recently, Lifelines data helped reveal the mental health impact – anxiety, depression, and restlessness – of earthquakes on tens of thousands in Groningen. Now, they are seeking a new generation of participants aged 40 or younger residing in Groningen, Friesland, or Drenthe, who have family members already involved in the study to track hereditary patterns. Researchers hope to add a fourth generation to the existing three, leveraging the combined data of lifestyle and genetics.