The Pasteur Institute of Tunis has been officially designated a regional hub for wastewater and environmental surveillance (WES) for North Africa by the Africa CDC. This selection recognizes the institute’s capacity to bolster environmental monitoring across the region. The hub will focus on strengthening surveillance systems related to wastewater and the wider environment. This initiative aims to improve disease detection and public health preparedness. The partnership with the Africa CDC marks a significant step for the institute and Tunisia in advancing regional health security. The Pasteur Institute will play a crucial role in coordinating and expanding WES activities throughout North Africa. This designation underscores the importance of environmental monitoring in safeguarding public health on the continent.