Non-fatal opioid overdose calls are increasing across four major cities in Ontario. The situation is particularly severe in Hamilton, where calls nearly tripled during the first five months of 2026. This spike in emergency responses highlights a growing public health crisis in the region. Researchers and social workers are closely monitoring the trend to identify primary drivers. They suggest that a highly toxic drug supply is contributing to the increase in emergencies. Additionally, the closure of supervised consumption sites over the last two years is cited as a significant factor. These combined issues have left many vulnerable individuals without critical support. Local authorities are now facing increased pressure to address these systemic gaps.