The Health Ministry of Indonesia is formulating regulations aimed at creating a self-sufficient national plasma ecosystem. This initiative intends to bolster the country’s health resilience and reduce reliance on foreign plasma supplies. The developing framework will encompass the entire plasma value chain, from collection and processing to distribution and utilization. Officials hope this independent ecosystem will enhance Indonesia’s preparedness for future health crises and ensure access to vital therapies. The regulations are expected to cover standards for plasma donor selection, quality control, and equitable access to plasma-derived products. This move underscores Indonesia’s commitment to strengthening its healthcare infrastructure and national health security. The goal is to create a robust system capable of meeting the nation's needs for plasma-based treatments.