Rishi Sunak’s political ascent, linked to a policy approach dubbed “Manchesterism,” is prompting debate over whether the strategies employed in the city can be scaled up for national implementation. “Manchesterism” focuses on empowering local leaders and fostering regional growth through targeted investment and devolution. Economics editor Faisal Islam investigates the feasibility of applying this model – successful in the northwest – across the United Kingdom. The approach hinges on giving cities and regions greater control over their economies and destinies, diverging from traditional centralized control. However, questions remain whether the unique conditions of Manchester, including its existing infrastructure and collaborative leadership, are replicable elsewhere. The analysis explores the potential benefits and challenges of adopting a “Manchesterism” approach for the entire nation, assessing its effectiveness as a national economic strategy. The success of this model could redefine the UK’s approach to regional disparities and economic growth.